Jakarta (ANTARA) - Illustration—Before the emergence of atypical acute kidney disorder, most cases of renal failure in children were caused by congenital factors linked to kidney malformation before birth. (ANTARA/HO-Shutterstock)
The Indonesian Paediatric Society (IDAI) is investigating the causes behind the rapidly progressive atypical acute kidney disorder in children, IDAI executive board head Piprim Basarah Yanuarso informed on Tuesday.
"There are some cases where children without any kidney issues and (who) have a normally functioning kidney have suffered from rapidly progressive (kidney disorder)," Yanuarso said.
Before the emergence of atypical acute kidney disorder, most cases of renal failure in children were caused by congenital factors linked to kidney malformation before birth.
The atypical acute kidney disorder was detected following research on 180 children from 20 provinces who were diagnosed with the disorder in the past two months despite being born without congenital kidney issues, the IDAI head said adding, most of the affected children were 1 to 5 years old.
Symptoms of the disorder often present in the digestive system and include vomiting, fever, diarrhea, as well as acute respiratory infection, cough, and runny nose, he informed.
"Particularities of this disorder are fever and a sudden reduction in urine volume," Yanuarso highlighted.
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According to him, the normal urine production in children is one milliliter per kilogram of body weight per hour, which means a one-year-old weighing 10 kilograms must excrete 240 cc of urine in 24 hours.
Laboratory checks would come positive for an increase in urea, creatinine, and potassium in infants with acute kidney disorder, the IDAI head said.
"What is concerning is that the disorder is rapidly progressing from an otherwise healthy condition to a sudden zero urine," Yanuarsi added.
He affirmed that the IDAI and the Health Ministry are researching various diseases and substances, which could be a factor behind the rapidly progressing acute kidney disorder among children.
The factors studied in research so far have included adenovirus, leptospirosis, as well as the presence of diethylene glycol and ethylene glycol in syrup medication, similar to cases of kidney failure among infants reported earlier in the Gambia, he added.
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